资源与环境微生物技术

孔文涛

教授
博士/硕士生导师
个人简介 科研项目 学术论文 其他介绍
教育背景

2004/09-2010/07山东大学微生物专业博士

2000/09-2004/07山东大学生物科学专业学士


工作经历

2022/10至今山东大学微生物技术研究院教授

2017/02-2022/07美国伊利诺伊大学香槟分校生物工程系研究员

2011/09-2016/09美国伊利诺伊大学香槟分校生物工程系博士后

研究方向

1. 益生菌合成生物学

2. 生物被膜和活性生物材料

3. 细菌素及抗菌肽的设计、合成及应用

4. 细菌人工共生系统的设计和应用



科研项目

1.2023-2025,国家自然科学基金优秀青年基金(海外)

2. 2023-2027,国家重点研发计划生物大分子与微生物组专项

学术论文

Kong, W., Qian, Y., Stewart, P. S., & Lu, T. (2022). De novo engineering of a bacterial lifestyle program.Nature Chemical Biology, 1-10.

Kong, W., Meldgin, D. R., Collins, J. J., & Lu, T. (2018). Designing microbial consortia with defined social interactions.Nature Chemical Biology,14(8), 821-829.

Celik Ozgen, V.#,Kong, W.#, Blanchard, A. E., Liu, F., & Lu, T. (2018). Spatial interference scale as a determinant of microbial range expansion.Science advances,4(11), eaau0695.

Kong, W., Blanchard, A. E., Liao, C., & Lu, T. (2017). Engineering robust and tunable spatial structures with synthetic gene circuits.Nucleic acids research,45(2), 1005-1014.

Kong, W., Kapuganti, V. S., & Lu, T. (2016). A gene network engineering platform for lactic acid bacteria.Nucleic acids research,44(4), e37-e37.

Jeong, Y.,Kong, W., Lu, T., & Irudayaraj, J. (2023). Soft hydrogel-shell confinement systems as bacteria-based bioactuators and biosensors.Biosensors and Bioelectronics,219, 114809.

Qian, Y.,Kong, W., & Lu, T. (2021). Precise and reliable control of gene expression in Agrobacterium tumefaciens.Biotechnology and bioengineering,118(10), 3962-3972.

Ibarra-Sánchez, L. A.,Kong, W., Lu, T., & Miller, M. J. (2021). Efficacy of nisin derivatives with improved biochemical characteristics, alone and in combination with endolysin PlyP100 to control Listeria monocytogenes in laboratory-scale Queso Fresco.Food Microbiology,94, 103668.

Liu, F., Mao, J.,Kong, W., Hua, Q., Feng, Y., Bashir, R., & Lu, T. (2020). Interaction variability shapes succession of synthetic microbial ecosystems.Nature communications,11(1), 309.

Lu, W.#,Kong, W.#, Yang, P., & Kong, J. (2015). A one-step PCR-based method for specific identification of 10 common lactic acid bacteria and Bifidobacterium in fermented milk.International Dairy Journal,41, 7-12.

Liao, C., Seo, S. O., Celik, V., Liu, H.,Kong, W., Wang, Y., ... & Lu, T. (2015). Integrated, systems metabolic picture of acetone-butanol-ethanol fermentation by Clostridium acetobutylicum.Proceedings of the National Academy of Sciences,112(27), 8505-8510.

Kong, W., & Lu, T. (2014). Cloning and optimization of a nisin biosynthesis pathway for bacteriocin harvest.ACS synthetic biology,3(7), 439-445.(封面文章)

Kong, W.#, Celik, V.#, Liao, C., Hua, Q., & Lu, T. (2014). Programming the group behaviors of bacterial communities with synthetic cellular communication.Bioresources and Bioprocessing,1, 1-11.

Xu, Y., Kong, J., &Kong, W. (2013). Improved membrane protein expression in Lactococcus lactis by fusion to Mistic.Microbiology,159(Pt_6), 1002-1009.

Lu, W., Kong, J., &Kong, W. (2013). Construction and application of a food-grade expression system for Lactococcus lactis.Molecular biotechnology,54, 170-176.

Kong, W., Kong, J., Hu, S., Lu, W., Wang, K., & Ji, M. (2011). Enhanced expression of PCV2 capsid protein in Escherichia coli and Lactococcus lactis by codon optimization.World Journal of Microbiology and Biotechnology,27, 651-657.

其它介绍

人才称号

1.国家海外高层次青年专家

2. 山东大学杰出中青年学者(第一层次)