教育背景
博士起止时间： 2001-2004毕业院校：山东大学专业：微生物学
硕士起止时间：1994-1997毕业院校：上海医药工业研究院专业：微生物制药
学士起止时间：1990-1994毕业院校：山东大学专业：微生物工程
工作经历
起止时间 单位名称 专业技术职务
2005-2006 国家海洋局厦门第三海洋研究所 博士后（副研究员）
2007.01-2008.09 山东大学 讲师
2008.09-2015.09 山东大学 副教授
2015.09-至今 山东大学 教授
研究方向
1. 海洋微生物多样性，系统学及其可培养化技术
2. 海洋微生物生态功能及其环境适应机制
3. 海洋微生物酶学
科研项目
1. 2021-2024 大洋表层海水中富营养细菌与寡营养细菌共存与互作机制：以Pseudoalteromonas属和Brachybacterium属菌株为例 国家自然基金面上项目
2. 2017-2020 深海细菌及其分泌的M23家族蛋白酶在 深海肽聚糖再循环利用中的作用及机制研究 国家自然基金面上项目
3. 2012-2015 深海新型细菌胶原蛋白酶mycolysin对胶原蛋白 的降解机制及其C端新类型结构域的功能研究 国家自然基金面上项目
4. 2018-2021 极地微生物新型生物制品的研制及其应用潜力评价 国家重点研发计划项目课题
5. 2017-2021 海山区微生物多样性 国家科技基础资源调查专项课题子课题
代表性论文
1．Yan Wang, Hai-Nan Su, Hai-Yan Cao, Si-Min Liu, Shi-Cheng Liu, Xia Zhang, Peng Wang, Chun-Yang Li, Yu-Zhong Zhang, Xi-Ying Zhang*, Xiu-Lan Chen* (2022) Mechanistic insight into the fragmentation of type I collagen fibers into peptides and amino acids by a Vibrio collagenase. Applied and Environmental Microbiology, 88(7): e0167721.
2. Jian Li, Jun-Hui Cheng, Zhao-Jie Teng, Zhong-Zhi Sun, Xiao-Yan He, Peng Wang, Mei Shi, Xiao-Yan Song, Xiu-Lan Chen, Yu-Zhong Zhang, Xinmin Tian*, Xi-Ying Zhang* (2021) Taxonomic and enzymatic characterization ofFlocculibacter collagenilyticus gen. nov., sp. nov., a novel gammaproteobacterium with high collagenase production. Frontiers in Microbiology, 12: 621161.
3. Shan Zhang, Wei-Xiong Liu, Ning-Hua Liu, Xiao-Yan He, Hai-Nan Su, Chun-Yang Li, Yu-Zhong Zhang, Xiao-Yan Song, Xi-Ying Zhang* (2020).Antarcticimicrobium sediminis gen. nov., sp. nov., isolated from Antarctic intertidal sediment, transfer ofRuegeria lutea toAntarcticimicrobium gen. nov. asAntarcticimicrobium luteum comb. nov. International Journal of Systematic and Evolutionary Microbiology 70(4): 2624-2631.
4. Xiu-Lan Chen#, Jin-Yu Yang#, Xiao-Yu Zheng, Qi Sheng, Lei Wang, Yu-Zhong Zhang, Qi-Long Qin*, Xi-Ying Zhang* (2019) Tripeptides from casein are signal molecules to induce the expression of the extracellular protease MCP-01 gene in marine bacterium Pseudoalteromonas sp. SM9913. Frontiers in Microbiology, 10: 1354.
5 Ping-Yi Li, Qiong-Qiong Yao, Peng Wang, Yi Zhang, Yue Li, Yan-Qi Zhang, Jie Hao, Bai-Cheng Zhou, Xiu-Lan Chen *, Mei Shi, Yu-Zhong Zhang and Xing-Ying Zhang*, A novel subfamily esterase with a homoserine transacetylase-like fold but no transferase activity. Applied and Environmental Microbiology, 2017, 83(9): pii: e00131-17. SCI, 4.282 (IF)
6. Xi-Ying Zhang, Xiao-Xu Han, Xiu-Lan Chen, Hong-Yue Dang, Bin-Bin Xie, Qi-Long Qin, Mei Shi*, Bai-Cheng Zhou, Yu-Zhong Zhang (2015) Diversity of cultivable protease-producing bacteria in sediments of Jiaozhou Bay, China. Frontiers in Microbiology, 6: 1021.
7. Ping-Yi Li, Xiu-Lan Chen, Peng Ji, Chun-Yang Li, Peng Wang, Yi Zhang, Bin-Bin Xie, Qi-Long Qin, Hai-Nan Su, Bai-Cheng Zhou, Yu-Zhong Zhang, Xi-Ying Zhang* (2015) Interdomain hydrophobic interactions modulate the thermostability of microbial esterases from the hormone-sensitive lipase family. Journal of Biological Chemistry, 290(17): 11188-11198.
8. Chun-Yang Li, Xiu-Lan Chen, Qi-Long Qin, Peng Wang, Wei-Xin Zhang, Bin-Bin Xie, Hai-Nan Su, Xi-Ying Zhang*, Bai-Cheng Zhou, Yu-Zhong Zhang (2015) Structural insights into the multispecific recognition of dipeptides of deep-sea gram-negative bacteriumPseudoalteromonas sp. strain SM9913. Journal of Bacteriology, 197(6): 1125-1134.
9. Li-Yuan Ran, Hai-Nan Su, Ming-Yang Zhou, Lei Wang, Xiu-Lan Chen, Bin-Bin Xie, Xiao-Yan Song, Mei Shi, Qi-Long Qin, Xiuhua Pang, Bai-Cheng Zhou, Yu-Zhong Zhang*, Xi-Ying Zhang* (2014) Characterization of a novel subtilisin-like protease myroicolsin from deep sea bacteriumMyroides profundi D25 and molecular insight into its collagenolytic mechanism. Journal of Biological Chemistry, 289(9): 6041-6053.
10. Qi-Long Qin#, Xi-Ying Zhang#, Xu-Min Wang, Gui-Ming Liu, Xiu-Lan Chen, Bin-Bin Xie, Hong-Yue Dang, Bai-Cheng Zhou, Jun Yu, Yu-Zhong Zhang* (2010) The complete genome ofZunongwangia profunda SM-A87 reveals its adaptation to the deep-sea environment and ecological role in sedimentary organic nitrogen degradation. BMC Genomics, 11:247.
