教授 & 研究员

宋晓妍

教授
博士/硕士生导师
0531-88362590
个人简介 科研项目 学术论文 其他介绍
教育背景

博士 2003/09-2006/12 山东大学 微生物学

硕士 1995/09-1998/07 山东农业大学 生物化学

本科 1991/09-1995/07 山东农业大学 蚕学


工作经历

2012/04- 山东大学 副教授、教授

2007/07-2012/04 济南大学 讲师、副教授

1998/07-2003/08 山东农业大学 助教、讲师

研究方向

1.微生物资源与利用

2.微生物-植物相互作用

3.真菌次级代谢产物的生物合成及其生物学功能研究


科研项目

国家重点研发计划项目子课题,极地微生物酶的挖掘、应用潜力评价与制备技术,2022YFC2807503-3,2022.12-2026.11,主持

国家自然科学基金面上项目,木霉驱动的根际微生物群落变化及其生态机制的宏组学研究,31971535,2020. 1 -2023.12,主持

国家重点研发计划项目子课题,基于造礁珊瑚与微生物互作的岛礁生境修复技术与示范,2018YFC1406504-3,2018.08 -2021.12,主持

山东省重点研发计划,生姜专用药肥双效木霉菌剂及其应用技术的研究,2017GSF21106,2017.1-2018.12,主持

国家自然科学基金面上项目,木霉次级代谢产物Trichokonins生物合成基因簇的鉴定及Lae1因子对其生物合成的调控作用,31570042,2016.1-2019.12,主持

国家自然科学基金面上项目,木霉产生的Trichokonins促进植物根系生长的作用与机制,31270064,2013.1-2016.12,主持

863计划子课题,木霉多肽植物免疫调节剂的中试研究,2011AA09070403,2011.7-2014.7,主持

代表性论文

Yu-Qiang Zhang#, Shan Zhang#, Mei-Ling Sun, Hai-Nan Su, Hao-Yang Li, Kun-Liu, Yu-Zhong Zhang, Xiu-Lan Chen, Hai-Yan Cao*, Xiao-Yan Song*. Antibacterial activity of peptaibols fromTrichoderma longibrachiatumSMF2 against gram-negativeXanthomonas oryzaepv.oryzae, the causal agent of bacterial leaf blight on rice. Frontiers in Microbiology. 2022. 13:1034779.

Xiao-yan He, Na Li, Xiu-lan Chen, Yu-zhong Zhang, Xi-ying Zhang *, Xiao-yan Song*.Pedobacter indicussp.nov., isolated from deep-sea sediment. Antonie van Leeuwenhoek. 2020, 113: 357–364.

Mei-Ling Sun, Fang Zhao, Xing-Kun Zhang, Xi-Ying Zhang, Yu-Zhong Zhang, Xiao-Yan Song* & Xiu-Lan Chen*. Improvement of the production of an Arctic bacterial exopolysaccharide with protective effect on human skin cells against UV-induced oxidative stress. Appl Microbiol Biotechnol, 2020,104(11): 4863-4875.

Jin-Chao Shi#, Wei-Ling Shi#, Yan-Rong Zhou#, Xiu-Lan Chen, Yu-Zhong Zhang, Xia Zhang*, Wei-Xin Zhang* and Xiao-Yan Song*. The putative methyltransferase TlLAE1 is involved in the regulation of peptaibols production in the biocontrol fungusTrichoderma longibrachiatumSMF2. Front. Microbiol., 2020, 11:1267.

Xiao-Han Guo#, Ning Wang, Xiao-Xue Yuan, Xi-Ying Zhang, Xiu-Lan Chen, Yu-Zhong Zhang, Xiao-Yan Song*.Poseidonibacter antarcticussp.nov., isolated from Antarctic intertidal sediment. Int J Syst Evol Microbiol. 2019, 69(9):2717-2722.

Jin-Cheng Rong, Qian-Qian Cha, Xue-Bing Ren, Bin-Bin Xie, Xiao-Yan Song*, Complete genome sequence ofPseudoalteromonas espejianaDSM9414T, an amino-acid-requiring strain from seawater. Mar Genomics. 2018, 38:21-23.

Xiu-Lan Chen#, Ming Peng#, Jing Li#, Bai-Lu Tang, Xuan Shao, Fang Zhao, Chang Liu, Xi-Ying Zhang, Ping-Yi Li, Mei Shi, Yu-Zhong Zhang, Xiao-Yan Song*, Preparation and functional evaluation of collagen oligopeptide-rich hydrolysate from fish skin with the serine collagenolytic protease fromPseudoalteromonassp. SM9913. Sci Rep., 2017, 7(1): 15716

Wei-Ling Shi, Xiu-Lan Chen, Li-Xia Wang, Zhi-Ting Gong, Shuyu Li, Chun-Long Li, Bin-Bin Xie, Wei Zhang, Mei Shi, Chuanyou Li, Yu-Zhong Zhang and Xiao-Yan Song*. Cellular and molecular insight into the inhibition of primary root growth ofArabidopsisinduced by peptaibols, a class of linear peptide antibiotics mainly produced byTrichodermaspp. J Exp Bot., 2016,67: 2191-2205.

Fei Xu, Xi-Ying Zhang, Chang Liu, Mei Shi, Hai-Nan Su, Qi-Long Qin, Chen Xiu-Lan, Zhang Yu-Zhong, Song Xiao-Yan*.Subsaxibacter arcticussp.nov., isolated from Arctic intertidal sand. Int J Syst Evol Microbiol. 2016, 66(1):132-136.

Bin-Bin Xie, Dan Li, Wei-Ling Shi, Qi-Long Qin, Xiao-Wei Wang, Jin-Cheng Rong, Cai-Yun Sun, Feng Huang, Xi-Ying Zhang, Xiao-Wei Dong, Xiu-Lan Chen, Bai-Cheng Zhou, Yu-Zhong Zhang, Xiao-Yan Song*. Deep RNA sequencing reveals a high frequency of alternative splicing events in the fungus.Trichoderma longibrachiatum.BMC Genomics. 2015 Feb; 16(1): 54.

Bin-Bin Xie, Qi-Long Qin, Mei Shi, Lei-Lei Chen, Yan-Li Shu, Yan Luo, Xiao-Wei Wang, Jin-Cheng Rong, Zhi-Ting Gong, Dan Li, Cai-Yun Sun, Gui-Ming Liu, Xiao-Wei Dong, Xiu-Hua Pang, Feng Huang, Wei feng Liu, Xiu-Lan Chen, Bai-Cheng Zhou, Yu-Zhong Zhang*, Xiao-Yan Song*. Comparative Genomics Provide Insights into Evolution ofTrichodermaNutrition Style. Genome Biol Evol. 2014 Feb; 6(2): 379–390.

Hai-Yun Li, Yan Luo, Xiu-Sheng Zhang, Wei-Ling Shi, Zhi-Ting Gong, Mei Shi, Lei-Lei Chen, Xiu-Lan Chen, Yu-Zhong Zhang, Xiao-Yan Song*. Trichokonins from Trichoderma pseudokoningii SMF2 induce resistance against Gram-negativePectobacterium carotovorumsubsp.carotovorumin Chinese cabbage. FEMS Microbiol Lett. 2014 May;354(1):75-82.

所获专利

张玉忠,宋晓妍,时金超,周燕蓉,刘白雪,陈秀兰,刘巍峰,解彬彬,李平一,李春阳。一株过表达lae1基因的木霉工程菌及其构建方法和应用,ZL201610899151.4,

张玉忠,宋晓妍,石梅,解彬彬,陈秀兰,董小卫,史伟玲,巩志廷,王丽霞.拟康氏木霉SMF2菌株在促进植物生长中的应用,ZL201310289488.X